OTESALY® PLLAVoluFill is an advanced PLLA-PEG collagen stimulator that combines immediate volumizing effects with long-term collagen regeneration. By stimulating fibroblast activity and new collagen production, it helps restore volume, improve skin elasticity, and enhance facial contours for natural-looking, long-lasting rejuvenation.
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Product Name |
OTESALY® PLLAVoluFill Poly-L-Lactic Acid PLLA dermal filler |
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Product Type |
PLLAVoluFill |
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Form |
Lyophilized Powder |
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Composition |
PLLA-PEG Microspheres, Sodium Hyaluronate, Mannitol |
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Specification |
360mg/Vial |
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Reconstitution |
4–8mL Sterile Water for Injection. Do not use saline or any chloride- containing solution. (Optional) Add 1–2 mL of 2% lidocaine to reduce injection discomfort. |
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Duration |
>24 Months |
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Injection Depth |
Deep Dermis, Superficial or Deep Subcutaneous Tissue |
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Needle Size |
27G TW×1/2 |
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Treatment Areas |
Temples, cheeks, forehead, nose, nasolabial folds, dorsum of hands, buttock, thigh and other soft tissue volume deficit areas |
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Shelf Life |
2 Years |
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PLLA-PEG microspheres act as a collagen biostimulator that gradually activates fibroblasts and encourages long-term collagen regeneration. This process helps rebuild structural support and restore youthful volume naturally.
Sodium hyaluronate provides immediate hydration and volumizing support while enhancing treatment comfort and early visible improvement.
Mannitol functions as an antioxidant stabilizer, helping protect the product formulation and supporting overall treatment performance.




