The skin around the eyes is one of the first areas on the face to show signs of fatigue and aging. Common concerns about the eye area that patients seek aesthetic treatment for include dark circles, uneven skin tone, dehydration and compromised skin texture, all of which contribute to a look of exhaustion.
Dark circles continue to be difficult to treat as there are many causes, but there are more and more treatment options. The key to successful treatment is to know the root cause and choose the right active ingredients to combat the issues at hand.
Under-eye mesotherapy is gaining popularity among aesthetic practitioners. This technique provides active ingredients directly into the superficial dermis, which results in better skin hydration and improves.
It is important to understand the causes of dark circles are different before choosing any mesotherapy protocol.
1. Pigmented dark circles: These occur due to excess deposition of melanin around the eyes. It is usually caused by genetic factors, chronic rubbing, sun exposure or post-inflammatory hyperpigmentation.
2. Vascular dark circles: The thin skin under the eyes makes blood vessels under the skin visible and poor microcirculation. Usually these circles are blue, purple or reddish-brown.
3. Structural dark circles: The loss of volume, tear trough deformities and shadowing effects can accentuate the visual perception of dark circles even in the absence of any significant pigmentation.
4. Mixed type of dark circles: In most of the cases patients present with combination of problems like pigmentation, thinning skin, dehydration and structural changes which requires more holistic approach for treatment.
These differences allow the practitioner to select the best treatment strategy for the periorbital area and to avoid a one size fits all approach.
The skin around the eyes is one of the thinnest areas of the body and has a relatively low concentration of sebaceous glands. Thus, the active ingredients present in topical skincare products frequently do not arrive in the target tissues in sufficient quantities.
Another alternative is the mesotherapy of the under-eye, which consists of injecting selected ingredients directly into the superficial layers of the skin. Possible benefits include:
● Increases skin moisture
● Smoother skin texture
● A brighter complexion
● Improved collagen production
● Greater attention to the eye zone
Mesotherapy is not a one size fits all approach but provides the practitioner the ability to combine different active ingredients to customize treatments for the individual patient.
The causes of dark circles are pigmentation, dehydration, the thinning of the skin or the loss of tissue volume, and therefore the different components of mesoderm therapy will have different effects. As a rule, practitioners do not rely on one approach alone but rather combine a number of components to perform dark circle injections that are tailored to the individual patient’s particular causes.
Dark circles can be especially visible because the skin under our eyes thins with age, revealing the blood vessels beneath.
Ingredients that support collagen production help to improve the density and elasticity of skin, thus strengthening the under-eye area and encouraging a healthier look.
Such formulations are frequently used to tackle the following issues:
● Skin under the eyes thin and fragile
● Visible blood vessels causing dark circles
● Loss of skin elasticity
● Initial signs of skin ageing
Chloasma (pigmentation-related dark circles) generally means too much melanin and uneven skin tone. In these cases, moisturizing alone is not enough to fix the problem.
Vitamin C is often added to formulas for skin brightening due to its antioxidant and skin brightening meso properties.
Other common brightening ingredients are:
● Tranexamic acid
● Glutathione
● Extract of arbutin
● Complexes of vitamins
These ingredients work synergistically together to help:
● Enhances complexion
● Skin tone blurring
● Dull skin improvement
● Boost skin luminosity
Many patients have more than one type of dark circles at the same time and often have symptoms of dehydration, dullness, thinning skin and pigmentation.
In these cases, Skinbooster treatments enhance the effects of targeted mesotherapy ingredients by improving the overall quality and hydration of the skin.
Skinboosters are often used for:
● Improve skin hydration
● Increases skin glow
● Enhance skin smoothness and elasticity
● Overall rejuvenation of the eye area
One of the most common concerns of the skin around the eyes is dehydration. Dry, weary skin can also make dark circles appear worse and fine lines more obvious.
Dermal fillers containing hyaluronic acid (HA) fill in hollows around the eyes, and absorb and retain moisture, thus improving hydration, enhancing smoothness, and refining overall texture of the skin.
For those with these problems:
● Dry skin around the eyes
● First signs of aging
● Subtle tear trough shadowing
● Skin looking dull and face looking tired
Rather than recommending one product, practitioners can often achieve better therapeutic results by combining products with different formulations tailored to the patient’s condition.
● OTESALY® Collagen Lift Solution: Boosts collagen synthesis, enhances skin firmness and elasticity, decreases fine lines around the eyes and reduces eye bags.
● OTESALY® Skin Whitening and W-PDRN: Designed to lighten and even out skin tone.
● OTESALY® Skinbooster: Rejuvenates the glow and hydration of dull skin, improves the appearance of fine lines around the eyes.
● OTESALY® Hydrofill: Deep hydration to the eye area, filling in hollows and overall skin texture improvement.
The combination of these products enables the practitioner to develop a personalized periorbital treatment plan to address the many patient needs and to expand other options.
|
Dark Circle Type |
Main Cause |
Recommended Ingredient |
OTESALY Solution |
|
Pigmented |
Excess melanin |
Vitamin C, Brightening Complexes |
Whitening |
|
Vascular |
Thin skin, visible vessels |
Collagen-Supporting Ingredients |
Collagen |
|
Structural |
Volume loss, dehydration |
Hyaluronic Acid |
Hydrofill |
|
Mixed |
Multiple contributing factors |
Combination Protocol |
Hydrofill + Whitening + Skin Booster |
It is often hard to achieve optimal therapeutic results with one ingredient alone. The focus of practitioners should be on the following aspects:
1. Accurate assessment: Determine the exact reason for the patient’s periorbital issues (e.g. pigmentation, visible vessels, dry skin, structural problems).
2. Ingredient selection: Select ingredients according to the main root causes and not just a “one-size-fits-all” treatment for all types of dark circles.
3. Continuation of treatment: Most patients see their best results with a series of treatment sessions, as well as good daily skin care.
4. Managing Patient Expectations: While mesotherapy can enhance the appearance of dark circles, the precise results will differ based on the patient’s anatomy and the root causes.
At a partner clinic in Southeast Asia, patients with mixed-type dark circles were treated with a combination of W-PDRN and collagen injections. They said after 3 treatment sessions (with two weeks apart):
● Up to 80% of patients showed a significant reduction in pigmentation.
● 75% of patients experienced an improvement in skin texture and thickness.
● Patient satisfaction was over 90%.
Another partner in Latin America worked on vascular dark circles with a skin booster protocol. They observed a significant increase in periocular hydration and a significant fading of the characteristic bluish-purple vascular discoloration.
These are not isolated results, but rather the clinical efficacy of scientifically formulated mesotherapy products administered by skilled practitioners.
Dark circles can be one of the most challenging problems in aesthetic medicine. They can be caused by pigmentation, visible blood vessels, dehydration, volume loss or a combination of these factors.
So successful periocular mesotherapy is not about one “magic” ingredient, but about choosing the right cocktail of hydrating, collagen-stimulating and brightening treatments for each patient’s individual needs.
The accurate assessment, along with the targeted mesotherapy formulas, enable practitioners to design personalized treatment plans for brighter, healthier and revitalized skin around the eyes.
FAQ
Q1：Does mesotherapy work for dark circles?
A：It is effective. Clinical studies have confirmed that under-eye mesotherapy outperforms traditional methods, such as chemical peels, in improving pigmentation. By directly injecting active ingredients into the dermal layer around the eyes, it precisely addresses root causes—such as visible blood vessels, pigment deposition, and skin thinning—and is recognized as the gold standard for periorbital treatment.
Q2：What ingredients actually work for dark circles?
A：The core active ingredients include collagen, hyaluronic acid (filling tear troughs, corresponding to hyaluronic acid eye treatment), vitamin C + tranexamic acid (suppressing melanin, optional vitamin C meso ampoule) and glutathione + arbutin (synergistically brightening). The compound skin brightening meso can simultaneously improve pigment, blood vessel and structural problems.
Q3：How to erase dark circles under eyes permanently?
A：Permanent results are difficult to achieve, but through collagen injection and hyaluronic acid filling, it can be maintained for 12 to 18 months. It is recommended to perform skin booster eye area maintenance every six months after the initial treatment, combined with OTESALY whitening injection and HA fillers, to achieve long-term management.
Q4：What deficiency causes dark circles?
A：Deficiencies in iron, vitamin B12, or vitamin K can exacerbate symptoms; however, most cases of stubborn dark circles stem from skin thinning and microcirculatory impairment. Since oral supplements alone offer limited efficacy, under-eye mesotherapy is required to deliver active ingredients directly to the target area and address the issue at its source.
